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Clinicaltrials.gov was searched for registered research protocols. The keyword phrases “palmitoylethanolamide” and “soreness” resulted in thirteen entries, of which three were done. None of these fulfilled our eligibility criteria.Costa and colleagues [178] have instructed that PEA was able to lessen mechanical allodynia and thermal hyperal
PPAR‐α is often a nuclear receptor protein that belongs for the household of PPARs and functions as transcription aspect regulating gene expression (Issemann and Eco-friendly, 1990).The exogenous administration of PEA may possibly in these kinds of cases provide to replenish amounts of endogenous PEA, restoring its protective, anti-inflammatory